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Article

MMP13, TIMP2 and TGFB3 Gene Polymorphisms in Brazilian Chronic Periodontitis and Periimplantitis Subjects.

Brazilian dental journal - 1 Jan 2000

Gonçalves Junior Roberto, Pinheiro Aristides da Rosa, Schoichet José Jorge, Nunes Carlos Henrique Ramirez, Gonçalves Rackel, Bonato Leticia Ladeira, Quinelato Valquiria, Antunes Leonardo Santos, Küchler Erika Calvano, Lobo Julie, Villas-Bôas Ricardo de Mello, Vieira Alexandre Rezende, Granjeiro José Mauro, Casado Priscila Ladeira

Abstract excerpt

Subjects susceptible to chronic periodontitis (CP) show a high risk for the development of periimplantitis (PI). Both diseases are multifactorial, presenting similarities in their pathophysiology and polygenic profile. MMP-13 (matrix metalloproteinases 13/ collagenase 3) is a collagenolytic enzyme, which expression is induced by TGF beta 3 (transforming growth factor type 3) in human gingival fibroblasts and...

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Source

Identifiers

PMID: 27058373
DOI: 10.1590/0103-6440201600601

Genes

MMP13
TGFB3
TIMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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