Article
MMP-1 promoter polymorphism: association with chronic periodontitis severity in a Brazilian population.
Journal of clinical periodontology - 1 Feb 2003
de Souza A P, Trevilatto P C, Scarel-Caminaga R M, Brito R B, Line S R P
Abstract excerpt
BACKGROUND: A single nucleotide polymorphism was described in the promoter region of the human MMP-1 gene, and this polymorphism has been associated with risk of cancer metastasis and inflammatory diseases. In this paper, we studied the possible relationship between the MMP-1 promoter polymorphism and the severity of chronic periodontitis. METHODS: Genomic DNA from oral mucosa was amplified by PCR and analyzed by...
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