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Article

Association of matrix metalloproteinase (MMP-1, MMP-3 and MMP-9) and cyclooxygenase-2 gene polymorphisms and their proteins with chronic periodontitis.

Archives of oral biology - 1 Oct 2011

Loo Wings T Y, Wang Min, Jin L J, Cheung Mary N B, Li G R

Abstract excerpt

AIMS: The objective of this study was to investigate the association amongst the single nucleotide polymorphisms of genes encoding for matrix metalloproteinase (MMP) 1, 3, 9 and cyclooxygenase-2 (COX-2) of subjects. Protein production of MMPs, COX-2 and Vascular Endothelial Growth Factor (VEGF) were also investigated. METHODS: 280 chronic periodontitis patients and 250 periodontitis-free subjects were selected....

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PMID: 21481333
DOI: 10.1016/j.archoralbio.2011.03.011

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