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Article

The monoclonal antibody 41H16 detects the Leu 4 responder form of human Fc gamma RII.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 1990

Gosselin E J, Brown M F, Anderson C L, Zipf T F, Guyre P M

Abstract excerpt

Human FcR for IgG can be divided into three classes (Fc gamma RI, II, and III) based on their structure and reactivity with mAb. Fc gamma RII can be further subdivided into two categories based on functional and biochemical assays. These two Fc gamma RII subtypes were initially recognized by the failure of T cells from 40% of individuals to proliferate in response to mAb Leu 4 (mouse IgG1, anti-CD3), a response...

Topics

Alleles
Antibodies, Monoclonal
Antibody Specificity
Antigens, CD
Antigens, Differentiation
Binding, Competitive
Blood Platelets
Epitopes
Humans
Lymphocyte Activation
Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Monocytes

Neutrophils

Receptors, Fc

Receptors, IgG

Source

Identifiers

PMID: 1689755

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1689755-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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