T cell proliferative response to interleukin 2: different frequency of responders among CD45R0 and CD45RA subsets.

doi:10.1016/0008-8749(90)90240-r

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Article

T cell proliferative response to interleukin 2: different frequency of responders among CD45R0 and CD45RA subsets.

Cellular immunology - 1 Nov 1990

Chinn A, Cosyns M, Hayward A R

Abstract excerpt

A proportion of human blood T cells is known to proliferate in cultures containing 10 or more units/ml of interleukin (IL)2, in the absence of exogenously added antigen. A possible explanation for this phenomenon is that the IL2 serves to maintain the proliferation of memory T cells which have recently been activated by antigen in vivo. To test this possibility we therefore separated T cells according to their...

Topics

Adult
Antigens, CD
Antigens, Differentiation
Antigens, Surface
Cell Division
DNA
Histocompatibility Antigens
Humans
Immunologic Memory
In Vitro Techniques
Infant, Newborn

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interleukin-2

Leukocyte Common Antigens

Leukocytes, Mononuclear

Lymphocyte Activation

Lymphocyte Depletion

Phenotype

Receptors, Antigen, T-Cell

Source

Open in PubMed

Identifiers

PMID: 2146031
DOI: 10.1016/0008-8749(90)90240-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2146031-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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