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Article

Paired overexpression of ErbB3 and Sox10 in pilocytic astrocytoma.

Journal of neuropathology and experimental neurology - 1 Aug 2006

Addo-Yobo Steven O, Straessle Jennifer, Anwar Adil, Donson Andrew M, Kleinschmidt-Demasters B K, Foreman Nicholas K

Abstract excerpt

Pilocytic astrocytoma (PA) is the most common glioma of childhood. Despite their relatively high incidence, the molecular mechanisms responsible for tumorigenesis and growth of PA are poorly understood. Previous in vitro studies in our laboratory showed that despite the absence of ErbB1, PA was sensitive to ErbB1 tyrosine kinase inhibitor gefitinib. To identify alternative targets of gefitinib in PA, we studied...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16896310
DOI: 10.1097/01.jnen.0000229989.25171.aa

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Paired overexpression of ErbB3 and Sox10 in pilocytic astrocytoma.PMID 16896310Read ↗

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Real-time quantitative polymerase chain reaction (qPCR) analysis with fluorescence resonance energy transfer (FRET) probes reveals differential expression of the four ERBB4 juxtamembrane region variants between medulloblastoma and pilocytic astrocytoma.Semantic proximity Read ↗

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An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice.Semantic proximity Read ↗

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A Sox10 expression screen identifies an amino acid essential for Erbb3 function.Semantic proximity Read ↗

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