Article
Sorting signals required for trafficking of the cysteine-rich acidic repetitive transmembrane protein in Trypanosoma brucei.
Eukaryotic cell - 1 Aug 2006
Qiao Xugang, Chuang Bin-Fay, Jin Yamei, Muranjan Madhavi, Hung Chien-Hui, Lee Pei-Tseng, Lee Mary Gwo-Shu
Abstract excerpt
In trypanosomatids, endocytosis and exocytosis are restricted to the flagellar pocket (FP). The cysteine-rich acidic repetitive transmembrane (CRAM) protein is located at the FP of Trypanosoma brucei and potentially functions as a receptor or an essential component for lipoprotein uptake. We characterized sorting determinants involved in efficient trafficking of CRAM to and from the FP of T. brucei. Previous...
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