Article
A flagellum-specific calcium sensor.
The Journal of biological chemistry - 2 Dec 2005
Buchanan Kathryn T, Ames James B, Asfaw Sofya H, Wingard Jennifer N, Olson Cheryl L, Campana Patricia T, Araújo Ana Paula U, Engman David M
Abstract excerpt
The flagellar calcium-binding protein (FCaBP) of the flagellated protozoan Trypanosoma cruzi associates with the flagellar membrane via its N-terminal myristate and palmitate moieties in a calcium-modulated, conformation-dependent manner. This mechanism of localization is similar to that described for neuronal calcium sensors, which undergo calcium-dependent changes in conformation, which modulate the...
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