Article

Nicastrin-like, a Novel Transmembrane Protein from Trypanosoma cruzi Associated to the Flagellar Pocket

2021-06-28

Abstract excerpt

Nicastrin (NICT) is a transmembrane protein physically associated with the polytypical aspartyl protease presenilin that plays a vital role in the correct localization and stabilization of presenilin to the membrane-bound γ-secretase complex. This complex is involved in the regulation of a wide range of cellular events including cell signaling and the regulation of endocytosed membrane proteins for their tra...

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Literature Corpus work: ba0e5639-e1e5-5246-a4a8-b741bfbe14c0
DOI: 10.20944/preprints202106.0673.v1

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