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Article

Sequence requirements for trafficking of the CRAM transmembrane protein to the flagellar pocket of African trypanosomes.

Molecular and cellular biology - 1 Jul 2000

Yang H, Russell D G, Zheng B, Eiki M, Lee M G

Abstract excerpt

CRAM is a cysteine-rich acidic transmembrane protein, highly expressed in the procyclic form of Trypanosoma brucei. Cell surface expression of CRAM is restricted to the flagellar pocket of trypanosomes, the only place where receptor mediated endocytosis takes place in the parasite. CRAM can function as a receptor and was hypothesized to be a lipoprotein receptor of trypanosomes. We study mechanisms involved in...

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Identifiers

PMID: 10866671
DOI: 10.1128/MCB.20.14.5149-5163.2000
PMCID: PMC85964

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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