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Article

MLR-tagging: informative SNP selection for unphased genotypes based on multiple linear regression.

Bioinformatics (Oxford, England) - 15 Oct 2006

He Jingwu, Zelikovsky Alexander

Abstract excerpt

UNLABELLED: The search for the association between complex diseases and single nucleotide polymorphisms (SNPs) or haplotypes has recently received great attention. For these studies, it is essential to use a small subset of informative SNPs accurately representing the rest of the SNPs. Informative SNP selection can achieve (1) considerable budget savings by genotyping only a limited number of SNPs and...

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PMID: 16895924
DOI: 10.1093/bioinformatics/btl420

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