Article
Fast and robust association tests for untyped SNPs in case-control studies.
Human heredity - 1 Jan 2010
Allen Andrew S, Satten Glen A, Bray Sarah L, Dudbridge Frank, Epstein Michael P
Abstract excerpt
Genome-wide association studies (GWASs) aim to genotype enough single nucleotide polymorphisms (SNPs) to effectively capture common genetic variants across the genome. Even though the number of SNPs genotyped in such studies can exceed a million, there is still interest in testing association with SNPs that were not genotyped in the study sample. Analyses of such untyped SNPs can assist in signal localization,...
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