Article
Gag-Pol bearing a reverse transcriptase drug-resistant mutation influences viral genomic RNA incorporation into human immunodeficiency virus type 1 particles.
The Journal of general virology - 1 Sept 2006
Aguiar Renato S, Pereira Helena S, Costa Luciana J, Brindeiro Rodrigo M, Tanuri Amilcar
Abstract excerpt
The unspliced human immunodeficiency virus type 1 (HIV-1) RNA is both the messenger for Gag and Gag-Pol and the viral genomic RNA (vRNA) that is packaged into the virion. Although Gag alone is sufficient for the incorporation of vRNA into virus particles, Gag-Pol molecules play an important role...
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