Article
Expression of human immunodeficiency virus type 1 reverse transcriptase in trans during virion release and after infection.
Journal of virology - 1 Jun 1996
Ansari-Lari M A, Gibbs R A
Abstract excerpt
The normal reverse transcription of retroviral RNA is a complex process which depends on the orchestration of several steps throughout the virus life cycle. During the assembly of retroviruses, reverse transcriptase (RT) is directed into the virion as a component of the Gag-Pol polyprotein. In the maturation of the Gag-Pol polyprotein of human immunodeficiency virus type 1 (HIV-1), cleavage by the viral protease...
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