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Article

Incorporation of pol into human immunodeficiency virus type 1 Gag virus-like particles occurs independently of the upstream Gag domain in Gag-pol.

Journal of virology - 1 Jan 2004

Cen Shan, Niu Meijuan, Saadatmand Jenan, Guo Fei, Huang Yue, Nabel Gary J, Kleiman Lawrence

Abstract excerpt

By using particle-associated reverse transcriptase (RT) activity as an assay for Pol incorporation into human immunodeficiency virus type 1 (HIV-1) Gag virus-like particles (VLPs), it has been found that truncated, protease-negative, Gag-Pol missing cis Gag sequences is still incorporated into Gag VLPs, albeit at significantly reduced levels (10 to 20% of the level of wild-type Gag-Pol). In this work, we have...

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Identifiers

PMID: 14694138
DOI: 10.1128/jvi.78.2.1042-1049.2004
PMCID: PMC368740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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