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Article

Heterogeneous genetic alterations in sporadic nephrotic syndrome associate with resistance to immunosuppression.

Journal of the American Society of Nephrology : JASN - 1 Jan 2015

Giglio Sabrina, Provenzano Aldesia, Mazzinghi Benedetta, Becherucci Francesca, Giunti Laura, Sansavini Giulia, Ravaglia Fiammetta, Roperto Rosa Maria, Farsetti Silvia, Benetti Elisa, Rotondi Mario, Murer Luisa, Lazzeri Elena, Lasagni Laura, Materassi Marco, Romagnani Paola

Abstract excerpt

In children, sporadic nephrotic syndrome can be related to a genetic cause, but to what extent genetic alterations associate with resistance to immunosuppression is unknown. In this study, we designed a custom array for next-generation sequencing analysis of 19 target genes, reported as possible causes of nephrotic syndrome, in a cohort of 31 children affected by sporadic steroid-resistant nephrotic syndrome and...

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Identifiers

PMID: 25060053
DOI: 10.1681/ASN.2013111155
PMCID: PMC4279734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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