Article
Genetic structure of the dopamine receptor D4 gene (DRD4) and lack of association with schizophrenia in Japanese patients.
Journal of psychiatric research - 1 Nov 2007
Mitsuyasu Hiroshi, Kawasaki Hiroaki, Ninomiya Hideaki, Kinukawa Naoko, Yamanaka Takeharu, Tahira Tomoko, Stanton Vincent P, Springett Gregory M, Hayashi Kenshi, Tashiro Nobutada, Kanba Shigenobu
Abstract excerpt
In order to investigate the contribution of genetic variation in the human dopamine receptor D4 gene (DRD4) to the risk of developing schizophrenia, we carried out a genetic analysis of 27 polymorphisms in 216 schizophrenic patients and 243 healthy controls from the Kyushu region of Japan. Twenty-two single nucleotide polymorphisms (SNPs) and five insertion/deletion polymorphisms were analyzed in this study,...
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