Article
[Identification of susceptibility genes for age-related macular degeneration--a success story of molecular genetics].
Duodecim; laaketieteellinen aikakauskirja - 1 Jan 2009
Seitsonen Sanna, Onkamo Päivi, Immonen Ilkka, Järvelä Irma
Abstract excerpt
The number of persons over 70 years of age with advanced age-related macular degeneration in Finland can be estimated to be approximately 50,000. Milder forms are additionally present in a considerably larger group. Smoking and age are undisputed non-genetic risk factors of age-related macular degeneration. Of the genetic factors, polymorphisms of the complement factor H (CFH) and LOC387715 genes have a strong...
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