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Article

Rapid emergence of enfuvirtide resistance in HIV-1-infected patients: results of a clonal analysis.

Journal of acquired immune deficiency syndromes (1999) - 1 Sept 2006

Lu Jing, Deeks Steven G, Hoh Rebecca, Beatty George, Kuritzkes Benjamin A, Martin Jeffrey N, Kuritzkes Daniel R

Abstract excerpt

OBJECTIVES: To study the dynamics of enfuvirtide (T-20) resistance development in HIV-1-infected subjects. PATIENTS AND METHODS: Clonal analysis of gp41 sequences was performed on serial samples obtained from HIV-1-infected subjects with early virologic failure of T-20-based regimens. RESULTS: Enfuvirtide resistance mutations at codons 36 to 45 in the first heptad repeat of gp41 emerged within 2 weeks in most...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16885776
DOI: 10.1097/01.qai.0000234083.34161.55

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Rapid emergence of enfuvirtide resistance in HIV-1-infected patients: results of a clonal analysis.PMID 16885776Read ↗

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