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Article

Characterization of the Pilin Ortholog of the<i>Helicobacter pylori</i>Type IV<i>cag</i>Pathogenicity Apparatus, a Surface-Associated Protein Expressed during Infection

3 Aug 2006

Abstract excerpt

The Helicobacter pylori cag pathogenicity island (cag PAI) encodes components of a type IV secretion system (T4SS) involved in host interaction and pathogenicity. Previously, seven cag PAI proteins were identified as homologs of Agrobacterium tumefaciens Vir proteins, which form a paradigm T4SS. The T pilus composed of the processed VirB2 pilin is an external structural part of the A. tumefaciens T4SS. In H....

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PMID: 16885455
DOI: 10.1128/jb.00060-06

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