Article
Cag type IV secretion system: CagI independent bacterial surface localization of CagA.
PloS one - 1 Jan 2013
Kumar Navin, Shariq Mohd, Kumari Rajesh, Tyagi Rakesh K, Mukhopadhyay Gauranga
Abstract excerpt
Helicobacter pylori Cag type IV secretion system (Cag-T4SS) is a multi-component transporter of oncoprotein CagA across the bacterial membranes into the host epithelial cells. To understand the role of unique Cag-T4SS component CagI in CagA translocation, we have characterized it by biochemical and microscopic approaches. We observed that CagI is a predominantly membrane attached periplasmic protein partially...
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