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Genes Required for Assembly of Pili Associated with the Helicobacter pylori cag Type IV Secretion System

3 Jun 2014

Abstract excerpt

Helicobacter pylori causes numerous alterations in gastric epithelial cells through processes that are dependent on activity of the cag type IV secretion system (T4SS). Filamentous structures termed "pili" have been visualized at the interface between H. pylori and gastric epithelial cells, and previous studies suggested that pilus formation is dependent on the presence of the cag pathogenicity island (PAI). Thus...

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PMID: 24891108
DOI: 10.1128/iai.01640-14

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