Article
Global Regulatory Impact of ClpP Protease of<i>Staphylococcus aureus</i>on Regulons Involved in Virulence, Oxidative Stress Response, Autolysis, and DNA Repair
3 Aug 2006
Abstract excerpt
Staphylococcus aureus is an important pathogen, causing a wide range of infections including sepsis, wound infections, pneumonia, and catheter-related infections. In several pathogens ClpP proteases were identified by in vivo expression technologies to be important for virulence. Clp proteolytic complexes are responsible for adaptation to multiple stresses by degrading accumulated and misfolded proteins. In this...
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