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Article

Global transcriptional analysis of clpP mutations of type 2 Streptococcus pneumoniae and their effects on physiology and virulence.

Journal of bacteriology - 1 Jul 2002

Robertson Gregory T, Ng Wai-Leung, Foley Joseph, Gilmour Raymond, Winkler Malcolm E

Abstract excerpt

Streptococcus pneumoniae is an important human pathogen that contains single copies of genes encoding the ClpP and FtsH ATP-dependent proteases but lacks the Lon and HslV proteases. We constructed and characterized the phenotypes of clpP, clpC, and clpX deletion replacement mutants, which lack the ClpP protease subunit or the putative ClpC or ClpX ATPase specificity factor. A DeltaclpP mutant, but not a DeltaclpC...

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Identifiers

PMID: 12057945
DOI: 10.1128/JB.184.13.3508-3520.2002
PMCID: PMC135132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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