Article
Role of Clp Proteins in Expression of Virulence Properties of<i>Streptococcus mutans</i>
31 Jan 2009
Abstract excerpt
Mutational analysis revealed that members of the Clp system, specifically the ClpL chaperone and the ClpXP proteolytic complex, modulate the expression of important virulence attributes of Streptococcus mutans. Compared to its parent, the DeltaclpL strain displayed an enhanced capacity to form biofilms in the presence of sucrose, had reduced viability, and was more sensitive to acid killing. The DeltaclpP and...
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