Article
ClpC affects the intracellular survival capacity of Staphylococcus aureus in non-professional phagocytic cells.
Scientific reports - 7 Nov 2019
Gunaratnam Gubesh, Tuchscherr Lorena, Elhawy Mohamed I, Bertram Ralph, Eisenbeis Janina, Spengler Christian, Tschernig Thomas, Löffler Bettina, Somerville Greg A, Jacobs Karin, Herrmann Mathias, Bischoff Markus
Abstract excerpt
Invasion and persistence of bacteria within host cells requires that they adapt to life in an intracellular environment. This adaptation induces bacterial stress through events such as phagocytosis and enhanced nutrient-restriction. During stress, bacteria synthesize a family of proteins known as heat shock proteins (HSPs) to facilitate adaptation and survival. Previously, we determined the Staphylococcus aureus...
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