Article
Genotype and allele frequency of CYP2D6 in Tamilian population.
European journal of clinical pharmacology - 1 Oct 2003
Adithan C, Gerard N, Naveen A T, Koumaravelou K, Shashindran C H, Krishnamoorthy R
Abstract excerpt
OBJECTIVE: To assess the frequency of CYP2D6 *3, *4, *5 and *10 allelic variants in a South Indian population and compare the frequencies with other major populations. METHODS: Polymerase chain reaction (PCR) or PCR-restriction fragment length polymorphism (RFLP)-based methods were used to identify the CYP2D6 genotypes of 106 healthy unrelated male and female volunteers of Tamilian origin. The allele and genotype...
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