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Article

Increased large conductance calcium-activated potassium (BK) channel expression accompanied by STREX variant downregulation in the developing mouse CNS.

BMC developmental biology - 27 Jul 2006

MacDonald Stephen H-F, Ruth Peter, Knaus Hans-Guenther, Shipston Michael J

Abstract excerpt

BACKGROUND: Large conductance calcium- and voltage activated potassium (BK) channels are important determinants of neuronal excitability through effects on action potential duration, frequency and synaptic efficacy. The pore- forming subunits are encoded by a single gene, KCNMA1, which undergoes extensive alternative pre mRNA splicing. Different splice variants can confer distinct properties on BK channels. For...

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Identifiers

PMID: 16872513
DOI: 10.1186/1471-213X-6-37
PMCID: PMC1562363

Genes

KCNMA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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