Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Temporal and spatial mouse brain expression of cereblon, an ionic channel regulator involved in human intelligence.

Journal of neurogenetics - 1 Mar 2010

Higgins Joseph J, Tal Adit L, Sun Xiaowei, Hauck Stefanie C R, Hao Jin, Kosofosky Barry E, Rajadhyaksha Anjali M

Abstract excerpt

A mild form of autosomal recessive, nonsyndromal intellectual disability (ARNSID) in humans is caused by a homozygous nonsense mutation in the cereblon gene (mutCRBN). Rodent crbn protein binds to the intracellular C-terminus of the large conductance Ca(2+)-activated K(+)channel (BK(Ca)). An mRNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Aging
Share to Developmental Disabilities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Large-Conductance Calcium-Activated Potassium Channel alpha Subunits

Share to Nerve Tissue Proteins

Share to Peptide Hydrolases

Share to Ubiquitin-Protein Ligases

Source

Identifiers

PMID: 20131966
DOI: 10.3109/01677060903567849

Genes

KCNMA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20131966-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Temporal and spatial mouse brain expression of cereblon, an ionic channel regulator involved in human intelligence.PMID 20131966Read ↗

The CB <sub>1</sub> receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfallsSemantic proximity Read ↗

Protein expression pattern in cerebellum of Cav2.1 mutant, tottering-6j mice.Semantic proximity Read ↗

Differential Neuronal Targeting of a New and Two Known Calcium Channel β<sub>4</sub>Subunit Splice Variants Correlates with Their Regulation of Gene ExpressionSemantic proximity Read ↗

Increased large conductance calcium-activated potassium (BK) channel expression accompanied by STREX variant downregulation in the developing mouse CNS.Semantic proximity Read ↗

The Moonwalker mouse: new insights into TRPC3 function, cerebellar development, and ataxia.Semantic proximity Read ↗

The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls.Semantic proximity Read ↗

LRRC37B is a species-specific regulator of voltage-gated channels and excitability in human cortical neuronsSemantic proximity Read ↗

Reduced cytoplasmic MBNL1 is an early event in a brain-specific mouse model of myotonic dystrophySemantic proximity Read ↗

Distinct expression of C1q‐like family mRNAs in mouse brain and biochemical characterization of their encoded proteinsSemantic proximity Read ↗

Nacc1 Mutation in Mice Models Rare Neurodevelopmental Disorder with Underlying Synaptic Dysfunction.Semantic proximity Read ↗

Astrocytic abnormalities in brain-specific Cacna1c-deficient mice: Implications for BBB impairment in neuropsychiatric diseases associated with CACNA1C mutations.Semantic proximity Read ↗

Role of Per3, a circadian clock gene, in embryonic development of mouse cerebral cortexSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.