Article
Three allele combinations associated with multiple sclerosis.
BMC medical genetics - 26 Jul 2006
Favorova Olga O, Favorov Alexander V, Boiko Alexey N, Andreewski Timofey V, Sudomoina Marina A, Alekseenkov Alexey D, Kulakova Olga G, Gusev Eugenyi I, Parmigiani Giovanni, Ochs Michael F
Abstract excerpt
BACKGROUND: Multiple sclerosis (MS) is an immune-mediated disease of polygenic etiology. Dissection of its genetic background is a complex problem, because of the combinatorial possibilities of gene-gene interactions. As genotyping methods improve throughput, approaches that can explore multigene interactions appropriately should lead to improved understanding of MS. METHODS: 286 unrelated patients with definite...
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