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Article

Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race

26 Jul 2006

Abstract excerpt

Interferon (IFN)-alpha-based therapy for chronic hepatitis C is effective in fewer than 50% of all treated patients, with a substantially lower response rate in black patients. The goal of this study was to investigate the underlying host transcriptional response associated with interferon treatment outcomes. We collected peripheral blood mononuclear cells from chronic hepatitis C patients before initiation of...

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PMID: 16871572
DOI: 10.1002/hep.21267

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