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Article

Genomic scale analysis of racial impact on response to IFN-alpha.

Proceedings of the National Academy of Sciences of the United States of America - 12 Jan 2010

Pos Zoltan, Selleri Silvia, Spivey Tara L, Wang Jeanne K, Liu Hui, Worschech Andrea, Sabatino Marianna, Monaco Alessandro, Leitman Susan F, Falus Andras, Wang Ena, Alter Harvey J, Marincola Francesco M

Abstract excerpt

Limited responsiveness to IFN-alpha in hepatitis C virus (HCV)-infected African-Americans compared to European Americans (AAs vs. EAs) hinders the management of HCV. Here, we studied healthy non-HCV-infected AA and EA subjects to test whether immune cell response to IFN-alpha is determined directly by race. We compared baseline and IFN-alpha-induced signal transducer and activator of transcription (STAT)-1,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20080756
DOI: 10.1073/pnas.0913491107
PMCID: PMC2818915

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NUDT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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