Article
Two decades of cancer genetics: from specificity to pleiotropic networks.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2005
Grisendi S, Pandolfi P P
Abstract excerpt
Modeling cancer in mice has reached an even greater relevance in the field of hematological malignancies, due to the already advanced characterization of the molecular basis of many hematological disorders. These mouse models have often allowed us to achieve insight into the pathogenesis of the human disease as well as to test novel therapeutic modalities in preclinical studies. However, one of the most rewarding...
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