Article
Oncogene co-operation in leukaemogenesis.
Cancer surveys - 1 Jan 1992
Adams J M, Cory S
Abstract excerpt
The multistep development of haematopoietic malignancies, like other neoplasms, reflects sequential mutations that either activate proto-oncogenes or disrupt tumour suppressor genes. In a few spontaneous leukaemias or lymphomas, more than one mutation has now been identified, and the experimental...
Topics
- Animals
- Cell Cycle
- Gene Expression
- Humans
- Leukemia
- Leukemia, Experimental
- Mice
- Mutation
- Oncogenes