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Article

Generation of a mouse for conditional excision of progesterone receptor.

Genesis (New York, N.Y. : 2000) - 1 Aug 2006

Hashimoto-Partyka Minako K, Lydon John P, Iruela-Arispe M Luisa

Abstract excerpt

The progesterone receptor (PR) is required for several aspects of mammalian female reproduction. PR null mice have overlapping defects that preclude an understanding of its multiple functions in ovulation, pregnancy, mammary gland biology, and sexual behavior. We have generated a PR conditional excision (PRCE) allele in which loxP sites flank exon 1. Homozygous PRCE females are fertile and appear to be...

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Identifiers

PMID: 16868919
DOI: 10.1002/dvg.20227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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