Article
Insights from the study of animals lacking functional estrogen receptor.
Science (New York, N.Y.) - 2 Dec 1994
Korach K S
Abstract excerpt
Estrogen hormones produce physiological actions within a variety of target sites in the body and during development by activating a specific receptor protein. Hormone responsiveness for the estrogen receptor protein was investigated at different stages of development with the use of gene knockout techniques because no natural genetic mutants have been described. A mutant mouse line without a functional estrogen...
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