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Article

Estrogen receptor knock-out mice: molecular and endocrine phenotypes.

Journal of the Society for Gynecologic Investigation - 1 Jan 2000

Korach K S

Abstract excerpt

Using gene-targeting techniques, transgenic, knock-out (KO) mice, homozygous for the disrupted estrogen receptor alpha (alpha ERKO) and beta gene (beta ERKO) have been produced. Estrogen receptor (ER) beta expression does not appear to be dependent on ER alpha expression. Progesterone receptor (PR) mRNA is detected in alpha ERKO mice and appears to have both estrogen-independent and -dependent gene regulation....

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PMID: 10732323
DOI: 10.1016/s1071-5576(99)00057-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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