Article
Fine mapping of genetic susceptibility to polycystic ovary syndrome on chromosome 19p13.2 and tests for regulatory activity.
The Journal of clinical endocrinology and metabolism - 1 Oct 2006
Stewart D R, Dombroski B A, Urbanek M, Ankener W, Ewens K G, Wood J R, Legro R S, Strauss J F, Dunaif A, Spielman R S
Abstract excerpt
CONTEXT: Little is known about genes that contribute to polycystic ovary syndrome (PCOS). We previously found linkage and association of PCOS with the dinucleotide marker D19S884 in two independent sets of families; allele 8 of D19S884 confers increased risk. OBJECTIVE/DESIGN: The objectives of the study were: 1) use the transmission/disequilibrium test (TDT) to assess linkage and association between PCOS and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.