Article
Family-based analysis of candidate genes for polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism - 1 May 2010
Ewens Kathryn G, Stewart Douglas R, Ankener Wendy, Urbanek Margrit, McAllister Jan M, Chen Chen, Baig K Maravet, Parker Stephen C J, Margulies Elliot H, Legro Richard S, Dunaif Andrea, Strauss Jerome F, Spielman Richard S
Abstract excerpt
CONTEXT: Polycystic ovary syndrome (PCOS) is a complex disorder having both genetic and environmental components. A number of association studies based on candidate genes have reported significant association, but few have been replicated. D19S884, a polymorphic marker in fibrillin 3 (FBN3), is one of the few association findings that has been replicated in independent sets of families. OBJECTIVE: The aims of the...
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