Article
Candidate gene region for polycystic ovary syndrome on chromosome 19p13.2.
The Journal of clinical endocrinology and metabolism - 1 Dec 2005
Urbanek M, Woodroffe A, Ewens K G, Diamanti-Kandarakis E, Legro R S, Strauss J F, Dunaif A, Spielman R S
Abstract excerpt
CONTEXT: Polycystic ovary syndrome (PCOS) is a common endocrine disorder that is believed to have a genetic basis. However, no specific susceptibility gene or region has been conclusively identified. OBJECTIVE: The objective of this study was to duplicate a previous study that localized a PCOS susceptibility region to chromosome 19p13.2 and to narrow the susceptibility region. DESIGN: This study was designed to...
Topics
- Adult
- Chromosome Mapping
- Chromosomes, Human, Pair 19
- Female
- Genetic Linkage
- Genetic Predisposition to Disease
- Humans
- Polycystic Ovary Syndrome
- Siblings
- Tandem Repeat Sequences
