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Article

Neuromuscular abundance of RB1CC1 contributes to the non-proliferating enlarged cell phenotype through both RB1 maintenance and TSC1 degradation.

International journal of molecular medicine - 1 Sept 2006

Chano Tokuhiro, Saji Masashi, Inoue Hirokazu, Minami Kahori, Kobayashi Toshiyuki, Hino Okio, Okabe Hidetoshi

Abstract excerpt

RB1-inducible coiled-coil 1 (RB1CC1) is a novel tumor suppressor implicated in the regulation of RB1 expression. It is abundant in post-mitotic neuromuscular cells, which are matured and enlarged, but scarce in smaller leukocytes, indicating an association between RB1CC1 status and cell size. To...

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Source

Identifiers

PMID: 16865226

Genes

TSC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16865226-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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