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Cell growth dilutes the cell cycle inhibitor Rb to trigger cell division

2018-11-14

Abstract excerpt

Cell size is fundamental to function in different cell types across the human body because it sets the scale of organelle structures, biosynthesis, and surface transport 1,2 . Tiny erythrocytes squeeze through capillaries to transport oxygen, while the million-fold larger oocyte divides without growth to form the ~100 cell pre-implantation embryo. Despite the vast size range across cell types, cells of a given ty...

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Literature Corpus work
241659d4-8973-5d34-a364-6e1a961ed430
DOI
10.1101/470013
Open publication

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Cell growth dilutes the cell cycle inhibitor Rb to trigger cell divisionDOI 10.1101/470013
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