Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Partitioning Viral Genomes in Mitosis: Same Idea, Different Targets

11 Jul 2006

Abstract excerpt

Papillomavirus infections are long-lived and persistent. The circular DNA of the viral genome is maintained in dividing epithelial cells as an extrachromosomal element. The E2 protein of the virus binds to the viral genome and tethers it to mitotic chromosomes to ensure that the genome is retained and faithfully partitioned in dividing cells. This mechanism has been best studied for bovine papillomavirus type 1....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to Cervical Cancer and HPV Research
Share to Plant Disease Resistance and Genetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16861919
DOI: 10.4161/cc.5.14.3094

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Partitioning Viral Genomes in Mitosis: Same Idea, Different TargetsPMID 16861919Read ↗

Viral Genome Tethering to Host Cell Chromatin: Cause and ConsequencesSemantic proximity Read ↗

Targeting mitotic chromosomes: a conserved mechanism to ensure viral genome persistenceSemantic proximity Read ↗

Variations in the association of papillomavirus E2 proteins with mitotic chromosomesSemantic proximity Read ↗

Interaction of the Betapapillomavirus E2 Tethering Protein with Mitotic ChromosomesSemantic proximity Read ↗

Human papillomavirus (HPV) origin-binding protein associates with mitotic spindles to enable viral DNA partitioningSemantic proximity Read ↗

E1 protein of bovine papillomavirus type 1 interferes with E2 protein-mediated tethering of the viral DNA to mitotic chromosomes.Semantic proximity Read ↗

The Human Papillomavirus Type 8 E2 Tethering Protein Targets the Ribosomal DNA Loci of Host Mitotic ChromosomesSemantic proximity Read ↗

Brd4 Is Required for E2-Mediated Transcriptional Activation but Not Genome Partitioning of All PapillomavirusesSemantic proximity Read ↗

Human Papillomavirus Genome Copy Number Is Maintained by S-Phase Amplification, Genome Loss to the Cytosol during Mitosis, and Degradation in G 1 PhaseSemantic proximity Read ↗

Interaction with TopBP1 Is Required for Human Papillomavirus 16 E2 Plasmid Segregation/Retention Function during MitosisSemantic proximity Read ↗

The Cellular DNA Helicase ChlR1 Regulates Chromatin and Nuclear Matrix Attachment of the Human Papillomavirus 16 E2 Protein and High-Copy-Number Viral Genome Establishment.Semantic proximity Read ↗

Analysis of chromatin attachment and partitioning functions of bovine papillomavirus type 1 E2 protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.