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Viral Genome Tethering to Host Cell Chromatin: Cause and Consequences

20 Jan 2016

Abstract excerpt

Viruses are small infectious agents that replicate in cells of a host organism and that evolved to use cellular machineries for all stages of the viral life cycle. Here, we critically assess current knowledge on a particular mechanism of persisting viruses, namely, how they tether their genomes to host chromatin, and what consequences arise from this process. A group of persisting DNA viruses, i.e....

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PMID: 26787361
DOI: 10.1111/tra.12378

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