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cMYB is involved in the regulation of fetal hemoglobin production in adults

13 Apr 2006

Abstract excerpt

A quantitative trait locus (QTL) controlling HbF levels has previously been mapped to chromosome 6q23 in an Asian-Indian kindred with beta thalassemia and heterocellular hereditary persistence of fetal hemoglobin (HPFH). Five protein-coding genes, ALDH8A1, HBS1L, cMYB, AHI1, and PDE7B reside in this 1.5-megabase (Mb) candidate interval of 6q23. To direct sequencing efforts we compared the expression profiles of...

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PMID: 16861354
DOI: 10.1182/blood-2006-01-008912

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cMYB is involved in the regulation of fetal hemoglobin production in adultsPMID 16861354Read ↗

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