Article
Characteristics of Human Leukocyte Antigen Class II Genes in Japanese Patients with Type 1 Diabetes and Autoimmune Thyroid Disease.
The Tohoku journal of experimental medicine - 9 Jul 2024
Kajita Risa, Takahashi Haruna, Yoshino Satoshi, Matsumoto Shunichi, Horiguchi Kazuhiko, Okada Shuichi, Yamada Masanobu, Yamada Eijiro
Abstract excerpt
Genetic factors, particularly human leukocyte antigen (HLA) class II genes, are known to significantly influence the onset of type 1 diabetes (T1D). Additionally, patients with T1D often develop autoimmune thyroid diseases (AITD). Despite this association, comprehensive research on individuals with both AITD and T1D in Japan, especially regarding the influence of specific HLA alleles, remains insufficient. In...
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