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Article

Analysis of the HLA and non-HLA susceptibility loci in Japanese type 1 diabetes.

Diabetes/metabolism research and reviews - 1 Nov 2011

Yamashita Hisakuni, Awata Takuya, Kawasaki Eiji, Ikegami Hiroshi, Tanaka Shoichiro, Maruyama Taro, Shimada Akira, Nakanishi Koji, Takahashi Kazuma, Kobayashi Tetsuro, Kawabata Yumiko, Miyashita Yumi, Kurihara Susumu, Morita-Ohkubo Tomoko, Katayama Shigehiro

Abstract excerpt

BACKGROUND: We previously reported the associations of human leukocyte antigen (HLA) (DRB1 and DQB1), INS, CTLA4, IL2RA, ERBB3 and CLEC16A with Japanese type 1 diabetes (T1D). In this study, we jointly analysed these loci in addition to IFIH1 and IL7R. METHODS: A maximum of 790 T1D patients and 953 control subjects were analysed. HLA was determined by sequencing-based typing. Seven non-HLA single nucleotide...

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Source

Identifiers

PMID: 22069271
DOI: 10.1002/dmrr.1234

Genes

ERBB3
INS
CTLA4
IFIH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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