Article
Cerebral cavernous malformations: clinical insights from genetic studies.
Neurosurgical focus - 15 Jul 2006
Mindea Stefan A, Yang Benson P, Shenkar Robert, Bendok Bernard, Batjer H Hunt, Awad Issam A
Abstract excerpt
Familial disease is responsible for one third to one half of cerebral cavernous malformation (CCM) cases presenting to clinical attention. Much has been learned in the past decade about the genetics of these cases, which are all inherited in an autosomal dominant pattern, at three known chromosome loci. Unique features of inherited CCMs in Hispanic-Americans of Mexican descent have been described. The respective...
Topics
- Animals
- Brain Neoplasms
- Cerebral Veins
- Disease Models, Animal
- Genetic Predisposition to Disease
- Hemangioma, Cavernous, Central Nervous System
- Hispanic or Latino
- Humans
- Inheritance Patterns
- Mice