Article
Association and linkage analyses of restriction fragment length polymorphisms for the human renin and antithrombin III genes in essential hypertension.
Journal of hypertension - 1 Sept 1991
Zee R Y, Ying L H, Morris B J, Griffiths L R
Abstract excerpt
Essential hypertension is a highly hereditable disorder in which genetic influences predominate over environmental factors. The molecular genetic profiles which predispose to essential hypertension are not known. In rats with genetic hypertension, there is some recent evidence pointing to linkage of renin gene alleles with blood pressure. The genes for renin and antithrombin III belong to a conserved synteny...
Topics
- Adult
- Aged
- Antithrombin III
- Autoradiography
- Female
- Genetic Linkage
- Genotype
- Humans
- Hypertension
- Male
- Middle Aged
- Pedigree
