Sib pair linkage analysis of renin gene haplotypes in human essential hypertension.

doi:10.1007/BF00197264

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Article

Sib pair linkage analysis of renin gene haplotypes in human essential hypertension.

Human genetics - 1 Jan 1992

Jeunemaitre X, Rigat B, Charru A, Houot A M, Soubrier F, Corvol P

Abstract excerpt

Although essential arterial hypertension is believed to have a strong genetic predisposition, the gene(s) responsible are unknown. The mechanisms underlying the regulation of blood pressure and experimental studies place the renin gene among the main candidate genes that need to be tested in huma...

Topics

Alleles
Case-Control Studies
Family
Genetic Linkage
Genotype
Haplotypes
Humans
Hypertension
Polymorphism, Restriction Fragment Length
Renin
Restriction Mapping

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